Osteoporosis Medication – Medication For Osteoporosis

Posted on November 30th, 2010

Osteoporosis is a syndrome that affects the density of bones, thereby making them brittle and prone to breakage. Preventing osteoporosis can be easy if you take proper care and use medication for osteoporosis . Osteoporosis can be caused by a number of different diseases and bodily changes. The most common reason for this syndrome is menopause, which explain why osteoporosis is far more common among elderly women than any other population group. Severe cases of osteoporosis are often caused by genetic defects.

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Osteoporosis Meds – Medication – Best Treatment For Osteoporosis

Certain medications have been associated with an increase in osteoporosis risk only steroids and anticonvulsants are classically associated but evidence is emerging with regard to other drugs.

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Steroid induced osteoporosis SIOP arises due to use of glucocorticoids analogous to Cushing s syndrome and involving mainly the axial skeleton. The synthetic glucocorticoid prescription drug prednisone is a main candidate after prolonged intake. Some professional guidelines recommend prophylaxis in patients who take the equivalent of more than mg hydrocortisone . mg of prednisolone especially when this is in excess of three months. Alternate day use may not prevent this complication.

1. Barbiturates phenytoin and some other enzyme inducing antiepileptics these probably accelerate the metabolism of vitamin D.
2. L Thyroxine over replacement may contribute to osteoporosis in a similar fashion as thyrotoxicosis does. This can be relevant in subclinical hypothyroidism.
3. Several drugs induce hypogonadism for example aromatase inhibitors used in breast cancer methotrexate and other anti metabolite drugs depot progesterone and gonadotropin releasing hormone agonists.
4. Anticoagulants long term use of heparin is associated with a decrease in bone density and warfarin and related coumarins have been linked with an increased risk in osteoporotic fracture in long term use.
5. Proton pump inhibitors these drugs inhibit the production of stomach acid it is thought that this interferes with calcium absorption. Chronic phosphate binding may also occur with aluminium containing antacids.
6. Thiazolidinediones used for diabetes rosiglitazone and possibly pioglitazone inhibitors of PPAR have been linked with an increased risk of osteoporosis and fracture.
7. Chronic lithium therapy has been associated with osteoporosis.

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Drugs, medicines and medication for Osteoporosis: Fosamax, Actonel, Evista and Miacalcin.

How To Prevent Osteoporosis

In some extreme cases osteoporosis is life threatening, and limits those that suffer by it to a life in wheelchair. When the condition is this bad, spine disorders are common, as the bone of the spine is no longer able to withstand the weight of the torso and head. Primary osteoporosis is usually related only to increasing age and decreasing bone mass. As we age, many changes occur in our body, physically, not for the better.

Osteoporosis is a common side effect of severe eating disorders eg.anorexia, extreme and lengthy ‘crash-dieting’ attempts at weight loss, and weight-loss surgery. In these cases, the cause is an inadequate dietary intake of calcium and a deficit in basic nutrition over a long period of time.

When it’s time to choose an osteoporosis medicine, you have lots of options. Here are 6 types of osteoporosis medicine to consider.

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Osteoporosis cannot be reversed, but once it is detected the progress of the disease can be slowed or halted by a very high intake of calcium and other minerals, such as Vitamin D. Daily proper dietary nutrition plays an important role. Keep in mind, caffeine can reduce calcium levels by causing diuresis. Excessive alcohol can decrease ostereoblast function.

To prevent and treat osteoporosis, the Food and Drug Administration (FDA) has approved medicines to reduce the risk of broken bones.

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About 44 millions Americans are threatened by osteoporosis. On top of that, it is reponsible for 1.5 millions fractures annually, concentrating directly on the vertebrae, hip, and wrist. About 50% of women and 25% of men are expected to have some kind of osteoporosis experience in their lifetime. So how much has it costed America to treat?? In 2001 alone, it was estimated at 17 billions was spent by hospitals and nursing homes indirectly. Fractures related to osteoporosis seem to be more common in Caucasians and Asians than other racial backgrounds. And if you are a woman, you are 4 times to be more at risk.

Signs and symptoms of Osteoporosis

Osteoporosis Drugs are available in the market and you may do exercises to prevent osteoporosis .

Osteoporotic fractures are those that occur in situations that would not lead to fractures in nonosteoporotic people. Typical fractures are vertebral fractures, hip fractures and those of the distal forearm. Collapse of vertebrae leads to chronic pain and characteristic bent statue, while the fractures of the long bones acutely impair mobility and may require surgery. Hip fracture, in particular, carries a poor prognosis.

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Facts About Osteoporosis

• Patients at risk for osteoporosis (e.g. steroid use) are generally treated with vitamin D and calcium supplements. In renal disease, a different form of Vitamin D (D3) is used, as the kidney cannot adequately synthesise D3 from precursors.
• In osteoporosis (or a very high risk), bisphosphonate drugs are prescribed. The most often prescribed bisphosphonate is sodium alendronate (Fosamax®) 10 mg a day or 70 mg once a week. Other commonly used treatments include risedronate (Actonel) and raloxifene (Evista).
• Recently, teriparatide (Forsteo®, recombinant parathyroid hormone) has been shown to be effective in osteoporosis, either alone or together with alendronate. Oral Strontium ranelate has also become available; this agent may also increase bone, rather than simply halting its breakdown.

Although many people need to take steroid medicines for health problems, they can cause bone loss and osteoporosis.

Information On Osteoporosis

Changes to lifestyle factors and diet are also recommended; the “at-risk” patient should include up to 1000mg of calcium in their diet (1500mg for a post-menopausal woman), which is roughly 3 servings of foodstuffs high in calcium daily. However, the benefit of supplementation of calcium alone remains to a degree controversial, since several nations with high calcium intakes through milk-products (e.g. the USA, Sweden) have some of the highest rates of osteoporosis worldwide.

A few studies even suggested an adverse affect of calcium excess on bone density and blamed the milk-industry for misleading customers. Some nutrionalists assert that excess consumption of dairy products causes acidification, which leaches calcium from the system, and argue that vegetables and nuts are a better source of calcium and that in fact milk products should be avoided. In any case, thirty minutes of weight-bearing exercise such as walking or jogging, three times a week, has been shown to increase bone mineral density, and reduce the risk of falls by strengthening the major muscle groups in the legs and back.

Patients with osteoporosis are at a high risk for additional fractures (the best predictor of fracture is a previous fracture). Treatment can improve fracture risk considerably.

Fractures can lead to decreased mobility and an additional risk of deep venous thrombosis and/or pulmonary embolism. Vertebral fractures can lead to severe chronic pain of neurogenic origin, which can be hard to control.

The pic depicting : Preventing Osteoporosis Bone Loss

Although osteoporosis patients have an increased mortality rate due to the complications of fracture, most patients die with the disease rather than of it.

Preventing Bone Loss In Osteoporosis

Bone density is a medical term referring to the amount of matter per cubic centimeter of bones. It is measured by a procedure called densitometry, often performed in the radiology or nuclear medicine departments of hospitals or clinics. The measurement is painless and non-invasive and involves minimal radiation exposure. Measurements are most commonly made over the lumbar spine and over the upper part of the hip. The forearm is scanned if either the hip or the lumbar spine can’t be.

Results are often reported in 3 terms:

1. Measured density in g/cm3
2. Z-score, the number of standard deviations above or below the mean for the patient’s age and se.x
3. T-score, the number of standard deviations above or below the mean for a healthy 30 year old adult of the same sex as the patient

The most common reason for measuring bone density is to screen for, or diagnose, osteoporosis.

The technique has several limitations.

1. Measurement can be affected by the size of the patient, the thickness of tissue overlying the bone, and other factors extraneous to the bones.
2. Bone density is a proxy measurement for bone strength, which is the resistance to fracture and the truly significant characteristic. Although the two are usually related, there are some circumstances in which bone density is a poorer indicator of bone strength.
3. Reference standards for some populations (e.g., children) are unavailable for many of the methods used.
4. Crushed vertebrae can result in falsely high bone density so must be excluded from analysis.

Reverse Osteoporosis Medicines

No medicines or medication available for reversing osteoporosis.

1. Osteoporosis Wikipedia the free encyclopedia – Osteoporosis Wikipedia the free encyclopedia
2. Bone Density at Wikipedia

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